Integrative RNA Biology
On May 2, 2023, Dr. Matvei Khoroshkin from Dr. Hani Goodarzi’s group at UCSF presented their recent preprint: https://www.biorxiv.org/content/10.1101/2023.03.11.532161v1 The manuscript describes a new approach the authors called “SwitchSeeker”, which allows for the identification of RNA structural switches in eukaryotes. SwitchSeeker generates secondary structures from sequence and draws on their…
The 2023 Annual RiboClub meeting will take place in Orford Québec, Canada from Sept 24 to 28 and features a great line-up of invited speakers: https://home.riboclub.org/annual-meeting/#upcoming
On Nov. 22, 2022, Christina Akirtava from Prof. Joel McManus’s lab at Carnegie Mellon University presented her and Gemma May’s latest work where they investigated how errors in genome annotations can lead to false positives. They’re intriguing story was also recently published in a Proceedings of the National Academy of…
EMBL-EBI Course | Introduction to RNA-seq and functional interpretation | 20 – 24 February 2023 Gain an introduction to the technology, data analysis, tools, and resources used in RNA sequencing and transcriptomics. The content will provide a broad overview of the subject area, and introduce participants to basic analysis of…
On May 4, 2022, Dr. Rasim Barutcu from the university of Toronto presented how he, co-first author Mingkun Wu and their colleagues applied APEX labeling to survey the distribution of RNA transcripts in the cell nucleus. The work led in Dr. Benjamin Blencowe’s lab at the University of Toronto…
Last week we had a terrific presentation by Dr. Kristopher Brannan, describing his recent first author paper on new technologies developed at Gene Yeo’s lab at UCSD for detecting RBP binding to RNA targets at single-cell resolution. The method Kris and his colleagues developed is called STAMP (“Surveying Targets by…
All the iRNA webinars from 2020, along with all other ISCB COSI webinars can be found (free of course!) in the following ISCBtv playlist – check it out! Reminder: If you want to directly go only to iRNA webinars you can simply follow the link below:
This year the iRNA got a concentration of abstracts on various aspects of RNA modifications (check out the schedule here). Indeed, epitranscriptomics is a 🔥 topic with many fundamental questions accompanied by both experimental and computational challenges. First, we organized a session to accommodate for the related talks. This then…
The APAeval hackathon was held during the 2021 RNA Society meeting (05/25/2021-06/05/21). APAeval’s aim is to benchmark 18 open-source, poly(A)-site-specific computational tools to provide users a basis for choosing the tools that best cater to their needs. The challenge is designed to be a collaborative effort of RNA biologists, bioinformaticians,…
APAeval is continuing! As we received lots of positive feedback after our successful hackathon @RNA2021, we decided to continue working on APAeval. Read more about our work in our status update published after the hackathon. If you’re interested to join in any form, just reach out to us at apaeval@irnacosi.org…