Seminars

iRNA Webinar 05.2023 with Dr. Matvei Khoroshkin, UCSF: A systematic search for RNA structural switches across the human transcriptome

On May 2, 2023, Dr. Matvei Khoroshkin from Dr. Hani Goodarzi’s group at UCSF presented their recent preprint: https://www.biorxiv.org/content/10.1101/2023.03.11.532161v1 The manuscript describes a new approach the authors called “SwitchSeeker”, which allows for the identification of RNA structural switches in eukaryotes. SwitchSeeker generates secondary structures from sequence and draws on their…

iRNA Webinar 11.2022 with Christina Akirtava, (McManus’s lab, CMU): False-positive IRESes, mRNA annotation errors, and a paradigm “unshift” in mammalian development

On Nov. 22, 2022, Christina Akirtava from Prof. Joel McManus’s lab at Carnegie Mellon University presented her and Gemma May’s latest work where they investigated how errors in genome annotations can lead to false positives. They’re intriguing story was also recently published in a Proceedings of the National Academy of…