News

iRNA Webinar 05.2023 with Dr. Matvei Khoroshkin, UCSF: A systematic search for RNA structural switches across the human transcriptome

On May 2, 2023, Dr. Matvei Khoroshkin from Dr. Hani Goodarzi’s group at UCSF presented their recent preprint: https://www.biorxiv.org/content/10.1101/2023.03.11.532161v1 The manuscript describes a new approach the authors called “SwitchSeeker”, which allows for the identification of RNA structural switches in eukaryotes. SwitchSeeker generates secondary structures from sequence and draws on their…

iRNA Webinar 11.2022 with Christina Akirtava, (McManus’s lab, CMU): False-positive IRESes, mRNA annotation errors, and a paradigm “unshift” in mammalian development

On Nov. 22, 2022, Christina Akirtava from Prof. Joel McManus’s lab at Carnegie Mellon University presented her and Gemma May’s latest work where they investigated how errors in genome annotations can lead to false positives. They’re intriguing story was also recently published in a Proceedings of the National Academy of…

ISCBtv channel for 2020 webinars

All the iRNA webinars from 2020, along with all other ISCB COSI webinars can be found (free of course!) in the following ISCBtv playlist – check it out! Reminder: If you want to directly go only to iRNA webinars you can simply follow the link below:

RNA Modifications Special Panel @ iRNA 2021, July 29th

This year the iRNA got a concentration of abstracts on various aspects of RNA modifications (check out the schedule here). Indeed, epitranscriptomics is a 🔥 topic with many fundamental questions accompanied by both experimental and computational challenges. First, we organized a session to accommodate for the related talks. This then…

The APAeval challenge – status update June 2021

The APAeval hackathon was held during the 2021 RNA Society meeting (05/25/2021-06/05/21). APAeval’s aim is to benchmark 18 open-source, poly(A)-site-specific computational tools to provide users a basis for choosing the tools that best cater to their needs. The challenge is designed to be a collaborative effort of RNA biologists, bioinformaticians,…

APAeval Challenge @ RNA 2021

APAeval is continuing! As we received lots of positive feedback after our successful hackathon @RNA2021, we decided to continue working on APAeval. Read more about our work in our status update published after the hackathon. If you’re interested to join in any form, just reach out to us at apaeval@irnacosi.org…